β-Catenin (CTNNB1) Promotes Preovulatory Follicular Development but Represses LH-Mediated Ovulation and Luteinization
نویسندگان
چکیده
منابع مشابه
Novel signaling pathways that control ovarian follicular development, ovulation, and luteinization.
The interactions of peptide and steroid hormone signaling cascades in the ovary are critical for follicular growth, ovulation, and luteinization. Although the pituitary gonadotropins follicle-stimulating hormone (FSH) and luteinizing hormone (LH) play key regulatory roles, their actions are also dependent on other peptide signaling pathways, including those stimulated by insulin-like growth fac...
متن کاملCetrorelix suppresses the preovulatory LH surge and ovulation induced by ovulation-inducing factor (OIF) present in llama seminal plasma
BACKGROUND The purpose of the study was to determine if the effect of llama OIF on LH secretion is mediated by stimulation of the hypothalamus or pituitary gland. METHODS Using a 2-by-2 factorial design to examine the effects of OIF vs GnRH with or without a GnRH antagonist, llamas with a growing ovarian follicle greater than or equal to 8 mm were assigned randomly to four groups (n = 7 per g...
متن کاملβ-catenin-mediated YAP signaling promotes human glioma growth
BACKGROUND Hippo/YAP pathway is known to be important for development, growth and organogenesis, and dysregulation of this pathway leads to tumor progression.We and others find that YAP is up-regulated in human gliomas and associated with worse prognosis of patients. However, the role and mechanism of YAP in glioma progression is largely unknown. METHODS The expression of YAP in glioma tissue...
متن کاملEffects of Rams and Luteal or Follicular Phase Ewes on Preovulatory LH Surge Characteristics in Ewes*
This study aimed to investigate whether the preovulatory LH surge mechanism is involved in sheep-to-sheep interaction for oestrous synchronisation. For that purpose, anoestrous ewes were inserted with intravaginal progestagen sponges for 13 days to induce ovulation. Upon sponge withdrawal, they were introduced either to 4 rams (n = 6, ram group), or to 4 ewes which were in follicular period (n ...
متن کاملSerum oestradiol and preovulatory follicular development before in-vitro fertilization.
Twenty-three in-vitro fertilization (IVF) treatment cycles (four unstimulated and 19 clomiphene-stimulated) were assessed retrospectively to discern relationships among serum oestradiol (OE2) titre on the day that human chorionic gonadotrophin (hCG) was given and the number and size of ovulatory follicles available for aspiration of oocytes during laparoscopy 32-38 h after hCG injection. Since ...
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ژورنال
عنوان ژورنال: Molecular Endocrinology
سال: 2010
ISSN: 0888-8809,1944-9917
DOI: 10.1210/me.2010-0141